| Primary Identifier | IPR030370 | Type | Family |
| Short Name | ABCA9 |
| description | Members of ABC (ATP-binding cassette) transporter subfamily A are full-length transporters [], which consist of a single long polypeptide chain organised into two tandemly arranged halves. Each half contains a membrane-spanning domain (MSD) followed by a cytoplasmic nucleotide binding domain (NBD) []. Human ABCA9 mRNA is induced during the differentiation of monocytes into macrophages and suppressed by cholesterol import, indicating that it is a cholesterol-responsive gene. ABCA9 is therefore likely to be involved in monocyte differentiation and macrophage lipid homeostasis []. |
