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Allele : Ptpn22<tm1Achn> protein tyrosine phosphatase, non-receptor type 22 (lymphoid); targeted mutation 1, Andrew C Chan
Primary Identifier  MGI:3043469 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptpn22
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 8, encoding the phosphatase domain, was replaced with a neo cassette via homologous recombination. Immunoblot analysis confirmed the absence of wild-type or truncated protein in thymocytes and splenocytes from homozygotes.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • pep(E8)-,
  • pep(E8)-,
  • pep-,
  • pep-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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