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Protein Coding Gene : Kif1c kinesin family member 1C
Primary Identifier  MGI:1098260 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  16562
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable ATP hydrolysis activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Acts upstream of or within retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Located in Golgi apparatus. Is expressed in alimentary system; hindbrain meninges; submandibular gland primordium; telencephalon; and vibrissa. Human ortholog(s) of this gene implicated in spastic ataxia 2. Orthologous to human KIF1C (kinesin family member 1C).
PHENOTYPE: Mice homozygous for a reporter allele are viable, fertile and overtly normal and display normal motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-36568,
  • Ltxs1,
  • RIKEN cDNA B430105J22 gene,
  • autoimmune orchitis resistance 3,
  • kinesin family member 1C,
  • lethal factor toxin susceptibility 1,
  • D11Bwg1349e,
  • N-3 kinsin,
  • B430105J22Rik,
  • MGI:2443544,
  • MGI:106361,
  • DNA segment, Chr 11, Brigham & Women's Genetics 1349 expressed,
  • Orch3,
  • MGI:1335095,
  • MGI:107988,
  • Kif1c
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2 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Function

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8 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

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Phenotype

Genes/Features --> Phenotypes (MP terms)

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