| Primary Identifier | MGI:1914321 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 67071 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ribosomal protein S6 kinase activity. Involved in negative regulation of ERK1 and ERK2 cascade; negative regulation of embryonic development; and negative regulation of mesoderm development. Is active in synapse. Is expressed in several structures, including axial skeleton thoracic region; genitourinary system; nervous system; nose; and respiratory system. Orthologous to human RPS6KA6 (ribosomal protein S6 kinase A6). PHENOTYPE: Male chimeras hemizygous for a gene trapped allele exhibit a possible gastrulation defect, primitive streak and node defects, failure of chorioallantoic fusion, impaired embryo turning, posterior truncation, abnormal heart development, and microcephaly. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
