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Protein Domain : Protein polyglycylase TTLL10

Primary Identifier  IPR027752 Type  Family
Short Name  TTLL10
description  TTLL10 is a polyglycylase, which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the γ-carboxyl groups of specific glutamate residues of target proteins []. It polyglycylates alpha tubulin and beta tubulin, but is not able to initiate glycylation and only has activity toward monoglycylated tubulin []. It has the ability to polyglycylate non-tubulin proteins such as NAP1; in this case it can initiate glycylation and does not require preliminary monoglycylation by another glycylase [].This family also includes , which is inactive [].

0 Child Features

1 Parent Features

9 Protein Domain Regions