| First Author | Dunn TL | Year | 1995 |
| Journal | Gene | Volume | 161 |
| Issue | 2 | Pages | 223-5 |
| PubMed ID | 7665083 | Mgi Jnum | J:28369 |
| Mgi Id | MGI:75988 | Doi | 10.1016/0378-1119(95)00280-j |
| Citation | Dunn TL, et al. (1995) Sequence and expression of Sox-18 encoding a new HMG-box transcription factor. Gene 161(2):223-5 |
| abstractText | The newly identified Sox gene family (Sry-like HMG-box gene) is characterized by a conserved DNA sequence encoding a domain of approx. 80 amino acids (aa) which is responsible for sequence-specific DNA binding. The first member isolated, the mammalian Y-linked testis-determining gene, Sry, is necessary and sufficient for male development. We report here the identification of two new members of this family, Sox-17 and 18. We have determined the full cDNA sequence of Sox-18 which encodes a protein of 378 aa. Sox-18 mRNA transcripts were restricted to heart, lung and skeletal muscle in the adult mouse. |
