| Primary Identifier | IPR025884 | Type | Domain |
| Short Name | MeCpG-bd_2/3_C_dom |
| description | CpG-methylation is a frequently occurring epigenetic modification of vertebrate genomes resulting in transcriptional repression. This domain is found at the C terminus of the methyl-CpG-binding domain (MBD) containing proteins MBD2 []and MBD3 []. The latter was shown to not bind directly to methyl-CpG DNA but rather interact with components of the NuRD/Mi2 complex [], an abundant deacetylase complex. |
