| First Author | Yoneya T | Year | 1997 |
| Journal | Gene | Volume | 194 |
| Issue | 2 | Pages | 241-7 |
| PubMed ID | 9272866 | Mgi Jnum | J:42334 |
| Mgi Id | MGI:1095613 | Doi | 10.1016/s0378-1119(97)00174-1 |
| Citation | Yoneya T, et al. (1997) Molecular cloning of a novel receptor-type protein tyrosine phosphatase from murine fetal liver. Gene 194(2):241-7 |
| abstractText | A cDNA fragment encoding a novel tyrosine phosphatase (PTPase), termed ptpf, was isolated from day 11.5 mouse fetal liver using reverse transcription-polymerase chain reaction (RT-PCR) with degenerate primers. The 5.5-kb cDNA encoding the complete coding region was isolated from an adult mouse kidney cDNA library. This cDNA contained a single open reading frame (ORF) encoding a predicted 1436-amino-acid protein with a molecular mass of 161,150 Da. Sequence analysis revealed that PTPf was homologous to PTPmu and PTPkappa, and a putative receptor-type PTPase. Northern blotting analysis of adult mouse mRNA indicated the existence of four major ptpf transcripts of approximately 10, 6, 3 and 2.7 kb, and these transcripts were expressed in a tissue-specific manner. During embryogenesis, only the 6-kb transcript was detected. |
