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Protein Coding Gene : Wnt11 wingless-type MMTV integration site family, member 11

Primary Identifier  MGI:101948 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  22411
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable enzyme activator activity and signaling receptor binding activity. Involved in heart development. Acts upstream of or within several processes, including Wnt signaling pathway; circulatory system development; and negative regulation of cell population proliferation. Located in extracellular matrix and extracellular region. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and limb. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma. Orthologous to human WNT11 (Wnt family member 11).
PHENOTYPE: Homozygous mutation of this gene results in extensive embryonic lethality and mutants surviving to birth die within the first 2 days of life. The kidneys are small and exhibit delayed development. [provided by MGI curators]
  • synonyms:
  • wingless-type MMTV integration site family, member 11,
  • Wnt11,
  • MGD-MRK-18782

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For