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Protein Coding Gene : Anapc7 anaphase promoting complex subunit 7

Primary Identifier  MGI:1929711 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  56317
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable enzyme-substrate adaptor activity and protein phosphatase binding activity. Predicted to be involved in several processes, including brain development; positive regulation of mitotic metaphase/anaphase transition; and protein K11-linked ubiquitination. Predicted to be located in nucleus and spindle. Predicted to be part of anaphase-promoting complex and heterochromatin. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Used to study syndromic intellectual disability. Orthologous to human ANAPC7 (anaphase promoting complex subunit 7).
PHENOTYPE: Mice homozygous for a null allele exhibit impaired swimming,difficulty moving on a pole, increased contextual freezing, and juvenile growth retardation. [provided by MGI curators]
  • synonyms:
  • APC7,
  • expressed sequence AW545589,
  • prediabetic NOD sera-reactive autoantigen,
  • MGI:2141217,
  • AW545589,
  • Anapc7,
  • anaphase promoting complex subunit 7

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

39 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For