Primary Identifier | MGI:4835063 | Allele Type | Transgenic |
Attribute String | Reporter | Gene | Tg(Tagln-LacZ)4Zli |
Strain of Origin | FVB | Is Recombinase | false |
Is Wild Type | false |
description | Three mouse lines were generated that expressed and transmitted the transgene, of which two were characterized. They are not named and no distinction is made among them in the primary reference. (J:34770) |
molecularNote | The transgene contains nucleotides -2126 through +65 (the end of exon 1) of the mouse transgelin/SM 22 promoter region driving expression of E. coli beta-galactosidase with a nuclear localization signal. In transgenic embryos, beta-galactosidase expression is detected in the somites and the presumptive right ventricle and outflow tract of the heart and subsequently in the arteries, but not in the visceral muscles or veins. In adults expression is seen in arterial smooth muscle cells, but not in other smooth muscles. |