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Protein Domain : AT-rich interactive domain-containing protein 3

Primary Identifier  IPR045147 Type  Family
Short Name  ARI3A/B/C
description  This entry represents a group of transcription factors, including ARID3A/B/C from humans and protein dead ringer (Retn) from Drosophila melanogaster. ARID3A (also known as E2FBP1 or Bright) is involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation [, ]. ARID3B has been linked to malignant neuroblastoma []. Retn is regulator of the late development of longitudinal glia []. Mutations in the Drosophila retn gene lead to female behavioral defects and alter a limited set of neurons in the CNS. Retn also affects a male behavioral pathway activated by fruM [].

0 Child Features

0 Parent Features

13 Protein Domain Regions