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Allele : Tg(Or4e5-cre)1Hsak transgene insertion 1, Hitoshi Sakano
Primary Identifier  MGI:6491953 Allele Type  Transgenic
Attribute String  Recombinase Gene  Tg(Or4e5-cre)1Hsak
Strain of Origin  Not Specified Is Recombinase  true
Is Wild Type  false
molecularNote  Cre recombinase gene is expressed under the control of upstream cis-acting DNA region of the mouse Olfr1507, 2-kb conserved homology region, mouse H element enhancer, which regulates odorant receptor (OR) gene cluster expression and Olfr1507 promoter. Due to the H enhancer activity, the Cre gene, now under the control of the Tg MOR28 promoter, is frequently chosen and activated for transcription in OSNs. The MOR28 promoter cannot be activated when any one of the endogenous OR genes is expressed first, due to OR-mediated negative feedback regulation.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(Olfr1507-cre)1Hsak,
  • Tg(Olfr1507-cre)1Hsak,
  • H-Cre,
  • Tg-H-Cre,
  • H-Cre,
  • Olfr1507Cre,
  • Olfr1507Cre,
  • Tg-H-Cre
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1 Feature

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0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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