| Primary Identifier | MGI:2679294 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 245522 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable metal ion binding activity. Acts upstream of or within noradrenergic neuron development and protein monoubiquitination. Located in neuronal cell body. Is expressed in nervous system and neural retina. Human ortholog(s) of this gene implicated in Miles-Carpenter syndrome. Orthologous to human ZC4H2 (zinc finger C4H2-type containing). PHENOTYPE: Mice homozygous or hemizygous for a knock-out allele exhibit neonatal lethality and ventral spinal cord patterning defects. About 50% of heterozygous females display postnatal growth retardation and fail to survive to adulthood, with some embryos exhibiting similar spinal cord patterning defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
