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Protein Coding Gene : Ddx6 DEAD-box helicase 6
Primary Identifier  MGI:104976 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  13209
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable mRNA binding activity and protein domain specific binding activity. Acts upstream of or within negative regulation of neuron differentiation and stem cell population maintenance. Located in P-body. Is expressed in several structures, including brain; early conceptus; neural tube; oocyte; and trunk somite. Orthologous to human DDX6 (DEAD-box helicase 6).
PHENOTYPE: Mice exhibit lethality prior to E11.5, decreased embryo size, embryonic growth retardation, caudal body truncation, and delayed primitive streak formation. [provided by MGI curators]
  • synonyms:
  • MGI:2444175,
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 6,
  • RIKEN cDNA C430015D01 gene,
  • E230023J21Rik,
  • 1110001P04Rik,
  • Ddx6,
  • MGD-MRK-31049,
  • RIKEN cDNA 1110001P04 gene,
  • MGI:1923546,
  • MGI:1925955,
  • HLR2,
  • p54,
  • C430015D01Rik,
  • rck,
  • DEAD-box helicase 6,
  • mRCK/P54,
  • RIKEN cDNA E230023J21 gene
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