| Primary Identifier | MGI:3610364 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 666794 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables mRNA 3'-UTR binding activity and pre-mRNA intronic binding activity. Involved in endocardial cushion development; positive regulation of skeletal muscle fiber differentiation; and regulation of mRNA metabolic process. Located in cytoplasm. Is expressed in several structures, including embryo mesenchyme; genitourinary system; limb bud; musculature; and sensory organ. Used to study dilated cardiomyopathy. Orthologous to human RBM24 (RNA binding motif protein 24). PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality between E12.5 and E13.5 with embryonic growth retardation, thin and unfused atrioventricular cushions, reduced myocardial trabeculation and increased apoptosis in the heart. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
