| Primary Identifier | MGI:1933227 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 83560 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable protein kinase binding activity. Involved in several processes, including intercellular bridge organization; mitotic spindle assembly checkpoint signaling; and nuclear chromosome segregation. Acts upstream of or within cellular response to leukemia inhibitory factor and negative regulation of cytokinesis. Located in intercellular bridge; kinetochore; and midbody. Is expressed in germ cell of ovary; germ cell of testis; ovary; and primordial germ cell of gonad. Human ortholog(s) of this gene implicated in spermatogenic failure 23. Orthologous to human TEX14 (testis expressed 14, intercellular bridge forming factor). PHENOTYPE: Males homozygous for a targeted allele are infertile due to spermatogenic failure. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
