| Primary Identifier | MGI:1316678 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 19355 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable double-stranded DNA 3'-5' DNA exonuclease activity. Predicted to be involved in DNA repair; cellular response to ionizing radiation; and negative regulation of cell cycle phase transition. Predicted to act upstream of or within DNA damage response. Predicted to be located in chromosome and nucleoplasm. Predicted to be part of checkpoint clamp complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system gland. Orthologous to human RAD1 (RAD1 checkpoint DNA exonuclease). PHENOTYPE: Mice homozygous for a knock-in allele exhibit normal B cell DNA damage sensitivity, somatic hypermutation, and class switch recombination. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
