Primary Identifier | MGI:5883222 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Otog |
Inheritance Mode | Recessive | Strain of Origin | C3HeB/FeJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This ENU-induced mutation was isolated in the Munich genome wide ENU recessive mutagenesis program. Gene mapping identified a one base pair substitution, a T36351 to C36351 transition at the splice donor site of intron 29, leading to a frame-shift of translation inducing an addition of 16 new amino acids at the carboxyl-terminus and a premature stop codon. |