Primary Identifier | MGI:2441890 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 338346 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable G protein-coupled receptor activity. Acts upstream of or within glucose homeostasis; negative regulation of insulin receptor signaling pathway; and regulation of growth. Predicted to be located in plasma membrane. Is expressed in cerebral cortex and cerebral cortex marginal layer. Orthologous to human GPR21 (G protein-coupled receptor 21). PHENOTYPE: Mice homozygous for a targeted allele exhibit improved glucose tolerance, insulin response and resistance to diet-induced obesity. [provided by MGI curators] |