| First Author | Jackson-Grusby LL | Year | 1987 |
| Journal | Nucleic Acids Res | Volume | 15 |
| Issue | 16 | Pages | 6677-90 |
| PubMed ID | 3628004 | Mgi Jnum | J:27240 |
| Mgi Id | MGI:74960 | Doi | 10.1093/nar/15.16.6677 |
| Citation | Jackson-Grusby LL, et al. (1987) A growth-related mRNA in cultured mouse cells encodes a placental calcium binding protein. Nucleic Acids Res 15(16):6677-90 |
| abstractText | We have characterized an mRNA that increases in abundance after serum stimulation of quiescent mouse fibroblasts. This mRNA, designated 18A2, encodes a predicted polypeptide of 101 amino acids with homology to known calcium binding proteins. A variety of mouse tissues express the 18A2 mRNA, with the highest levels detected in the non-pregnant uterus and in the placenta. The concentration of 18A2 mRNA in total placental RNA decreases from day 8 to day 10 of pregnancy, and is below detection throughout the latter half of gestation. In serum-stimulated fibroblasts, the increase in 18A2 mRNA is dependent on protein synthesis. The 18A2 mRNA is similar in size, serum-inducibility, and sequence to the 2A9 mRNA (1), but these mRNAs are derived from distinct genes. This suggests that the mouse genome harbors a family of serum-inducible genes encoding proteins predicted to bind calcium. |
