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Protein Coding Gene : Tdrkh tudor and KH domain containing protein

Primary Identifier  MGI:1919884 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  72634
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable RNA binding activity. Involved in fertilization; male gamete generation; and piRNA processing. Located in mitochondrion; pi-body; and piP-body. Is expressed in central nervous system; reproductive system; sensory organ; and urinary system. Orthologous to human TDRKH (tudor and KH domain containing).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility associated with arrested male meiosis, massive double-strand breaks and impaired piRNA biogenesis. [provided by MGI curators]
  • synonyms:
  • tudor and KH domain containing protein,
  • Tdrkh,
  • 2700091C21Rik,
  • RIKEN cDNA 2700091C21 gene,
  • Tdrd2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For