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Protein Coding Gene : Muc19 mucin 19

Primary Identifier  MGI:2676278 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  239611
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables hydroxyapatite binding activity. Acts upstream of or within several processes, including hemopoiesis; lymphocyte proliferation; and response to bacterium. Predicted to be located in extracellular region. Is expressed in sublingual gland; sublingual gland epithelium; and submandibular duct. Used to study Sjogren's syndrome. Orthologous to human MUC19 (mucin 19, oligomeric).
PHENOTYPE: Mice homozygous for this spontaneous mutation show a partially arrested mucous cell differentiation of the sublingual glands. Severe inflammatory lesions resembling Sjogren's syndrome develop spontaneously in salivary and lacrimal glands of neonatally thymectomized mutants without any immunization. [provided by MGI curators]
  • synonyms:
  • sublingual gland differentiation arrest,
  • apomucin,
  • mucin 19,
  • sld,
  • MGD-MRK-14437,
  • Muc19,
  • MGI:98316

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For