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Allele : Ift56<hop> intraflagellar transport 56; hop sterile

Primary Identifier  MGI:1856054 Allele Type  Spontaneous
Attribute String  Null/knockout Gene  Ift56
Inheritance Mode  Recessive Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The molecular lesion is a C-to-A point mutation (c.1290C>A) that changes a tyrosine codon to a stop codon (p.Y430*) in exon 15. This mutation arose spontaneously in an unirradiated stock at the MRC Radiobiology Unit at Harwell in 1967. RT-PCR indicates expression of the mRNA was reduced 5.7-fold compared to that of the wild-type mRNA in MEFs.
  • mutations:
  • Single point mutation
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele