| Primary Identifier | IPR032974 | Type | Family |
| Short Name | Polypren_kinase |
| description | Dolichol kinase catalyses the CTP-mediated phosphorylation of dolichol in eukaryotic cells, the terminal step in dolichyl monophosphate (Dol-P) biosynthesis de novo. Dol-P serves as a glycosyl carrier lipid in the assembly of N-linked glycoproteins, glycosylphosphatidylinositol anchors, and the C- and O-mannosylation of proteins in the endoplasmic reticulum (ER) of yeast and animal cells [, , ]. Phytol kinase catalyses the CTP-dependent phosphorylation of phytol to phytylmonophosphate (PMP) and has a role in tocopherol biosynthesis in plants [, ]. Both of these enzymes belong to the polyprenol kinase family. |
