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Protein Coding Gene : Tle3 transducin-like enhancer of split 3
Primary Identifier  MGI:104634 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  21887
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable transcription corepressor activity. Involved in negative regulation of cold-induced thermogenesis. Predicted to be located in nucleoplasm. Predicted to be part of beta-catenin-TCF complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human TLE3 (TLE family member 3, transcriptional corepressor).
PHENOTYPE: Mice homzoygous for a gene trap allele exhibit embryonic lethality. [provided by MGI curators]
  • synonyms:
  • Tle3,
  • RIKEN cDNA 2610103N05 gene,
  • Grg3b,
  • MGI:1917582,
  • Grg3a,
  • ESG,
  • MGD-MRK-26071,
  • 2610103N05Rik,
  • transducin-like enhancer of split 3,
  • mKIAA1547
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Canonical gene --> CDSs in specific strains.

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Canonical gene --> Transcripts in specific strains.

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