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Protein Coding Gene : Dusp26 dual specificity phosphatase 26

Primary Identifier  MGI:1914209 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  66959
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; p53 binding activity; and phosphoprotein phosphatase activity. Predicted to be involved in negative regulation of ERK1 and ERK2 cascade; negative regulation of transcription by RNA polymerase II; and positive regulation of cell adhesion. Located in mitochondrion. Is expressed in articular cartilage; limb; nervous system; neural retina; and spleen. Orthologous to human DUSP26 (dual specificity phosphatase 26).
PHENOTYPE: Mice homozygous for a floxed allele activated in hepatocytes exhibit increased susceptibility to diet-induxed non-nonalcoholic fatty liver disease. [provided by MGI curators]
  • synonyms:
  • dual specificity phosphatase 26,
  • RIKEN cDNA 2310043K02 gene,
  • Dusp26,
  • 2310043K02Rik

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

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Genes --> Homologs

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Expression

Gene --> Expression annotations

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Disease

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