| Type | MGI:General | Description | pIpC-treated mice show reduced formation of early B cell progenitors in the bone marrow ex vivo, Lin- cells co-cultured with OP9 stromal cells in the presence of IL7 and Flt3L (to promote B cell development) do not exhibit any B220+ B cell growth, suggesting that stem cells fail to differentiate into committed progenitor B cells |
