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Protein Domain : Very low-density lipoprotein receptor

Primary Identifier  IPR032931 Type  Family
Short Name  VLDLR
description  Very low-density lipoprotein receptor (VLDLR) mediates the binding and uptake of apoE-containing lipoproteins, such as VLDL and beta-VLDL []. It prevents the migration of retinal vascular endothelial cells into the photoreceptor cell layer and subretinal space []and mediates an anti-angiogenic signal in the retina []. It is involved in adipose tissue inflammation and mediates VLDL-induced lipid accumulation and induction of inflammation and ER stress in adipocytes and macrophages [].

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12 Protein Domain Regions