| First Author | Ziefer P | Year | 2002 |
| Journal | Brain Res Mol Brain Res | Volume | 101 |
| Issue | 1-2 | Pages | 132-5 |
| PubMed ID | 12007841 | Mgi Jnum | J:76913 |
| Mgi Id | MGI:2180596 | Doi | 10.1016/s0169-328x(02)00176-6 |
| Citation | Ziefer P, et al. (2002) Molecular cloning and expression of rat torsinA in the normal and genetically dystonic (dt) rat. Brain Res Mol Brain Res 101(1-2):132-5 |
| abstractText | Deletions within the TOR1A gene cause early-onset (DYT1) torsion dystonia. We have cloned and sequenced the rat cDNA homologue of TOR1A and found a 91% identity with the human sequence. Northern blot analysis detects a single transcript of approximately 1.5 kb. In situ hybridization reveals a widespread distribution of torsinA mRNA within brain. No mutations were identified in the coding region of the gene in the genetically dystonic (dt) rat. |
