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Protein Coding Gene : Atxn7l3 ataxin 7-like 3

Primary Identifier  MGI:3036270 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  217218
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable nuclear receptor coactivator activity. Predicted to be involved in positive regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleus. Predicted to be part of DUBm complex and SAGA complex. Orthologous to human ATXN7L3 (ataxin 7 like 3).
PHENOTYPE: Mouse embryonic stem cells homozygous for a knock-out allele exhibit strikingly increased H2B monoubiquitination (H2Bub) levels and fail to show loss of global H2Bub following inhibition of transcriptional elongation. [provided by MGI curators]
  • synonyms:
  • E030022H21Rik,
  • ataxin 7-like 3,
  • Atxn7l3,
  • RIKEN cDNA E030022H21 gene

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1 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Mouse features --> Functions (GO terms)

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