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Protein Coding Gene : Marf1 meiosis regulator and mRNA stability 1

Primary Identifier  MGI:2444505 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  223989
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable CCR4-NOT complex binding activity. Involved in female meiotic nuclear division; oogenesis; and regulation of gene expression. Acts upstream of or within double-strand break repair. Predicted to be located in Golgi apparatus and peroxisome. Predicted to be active in cytoplasm. Is expressed in central nervous system; early conceptus; oocyte; and sensory organ. Orthologous to human MARF1 (meiosis regulator and mRNA stability factor 1).
PHENOTYPE: Mice homozygous for an ENU-induced mutation exhibit female infertility with abnormalities in oogenic processes including meiotic progression, genomic integrity and acquisition of developmental competence. [provided by MGI curators]
  • synonyms:
  • expressed sequence C87306,
  • Marf1,
  • MGC:36956,
  • BC031575,
  • meiosis regulator and mRNA stability 1,
  • RIKEN cDNA 4921513D23 gene,
  • C87306,
  • MGI:2387606,
  • MGI:2146729,
  • 4921513D23Rik,
  • cDNA sequence BC031575

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