| Primary Identifier | MGI:2180369 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Asgr1 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance gene under the control of a pol2 promoter replaced the transcription initiation codon and the sequences encoding the transmembrane domain. Northern blot analysis showed an absence of normal transcipt in homozygous mutant mice. A truncated message was detected, however, Western blot analysis showed there to be no protein expression in homozygous mutant animals. |
