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Protein Coding Gene : Fgf17 fibroblast growth factor 17

Primary Identifier  MGI:1202401 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  14171
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Predicted to enable growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Acts upstream of or within fibroblast growth factor receptor signaling pathway and positive regulation of cell population proliferation. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including arterial system; central nervous system; embryo mesenchyme; nose; and skeleton. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 20 with or without anosmia. Orthologous to human FGF17 (fibroblast growth factor 17).
PHENOTYPE: Mice homozygous for disruptions in this gene are grossly normal at birth and apparently healthy at birth. However, there are tissue losses in the inferior colliculus and the anterior vermis of the brain. [provided by MGI curators]
  • synonyms:
  • fibroblast growth factor 17,
  • Fgf17

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Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

54 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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1 Driver For