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Protein Domain : WD repeat-containing protein 73

Primary Identifier  IPR042795 Type  Family
Short Name  Wdr73
description  WDR73 (WD repeat-containing protein 73) contains six WD40 repeats that form a six-bladed propeller structure. It is expressed in brain and kidney, localizing to spindle poles during mitosis. Mutations of the WDR73 gene cause Galloway-Mowat syndrome, a rare autosomal-recessive condition characterised by nephrotic syndrome associated with microcephaly and neurological impairment [, ].

0 Child Features

0 Parent Features

3 Protein Domain Regions