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Allele : Dcc<tm1Wbg> DCC netrin 1 receptor; targeted mutation 1, Robert A Weinberg

Primary Identifier  MGI:1934924 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dcc
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
description  Homozygous mutant mice have defective axonal projections of neural cells similar to those observed in null mutations for the netrin gene, Ntn1, but with no effects on intestine or on tumorigenesis within the intestine (J:39765).
molecularNote  A neomycin resistance cassette was inserted into exon 3. Immunoprecipitation experiments demonstrated that no full length protein was produced from this allele in homozygous mice.
  • mutations:
  • Insertion
  • synonyms:
  • Dcc<X3>,
  • Dcc<X3>,
  • Dcc-,
  • Dcc-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

76 Publication categories

Trail: Allele