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Allele : Rr15<tm1Wrk> regulatory region 15; targeted mutation 1, Wolf Reik
Primary Identifier  MGI:5301263 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout Gene  Rr15
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin selection cassette was inserted in "differentially methylated region 1" (DMR1) upstream of Igf2. Insertion was in HpaII site 4 located in a Lrrfip1 (GCF2) binding consensus sequence. Properly targeted mice were crossed to mice carrying Tg(Pgk1-cre)1Lni to excise the selection cassette and leave behind a single loxP site that disrupts the GCF2 binding element.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

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Phenotype

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