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Protein Domain : E3 ubiquitin-protein ligase Trim36

Primary Identifier  IPR027726 Type  Family
Short Name  Trim36
description  The tripartite motif-containing protein (Trim) family is defined by the presence of a common domain structure composed of a RING finger, a B-box, and a coiled-coil motif []. Trim36 is a E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. It interacts with centromere protein-H, one of the kinetochore proteins and is involved in chromosome segregation and cell cycle regulation [, ]. It may play a role in the acrosome reaction and fertilisation [, ].

0 Child Features

0 Parent Features

3 Protein Domain Regions