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Allele : Prkdc<tm1Fwa> protein kinase, DNA activated, catalytic polypeptide; targeted mutation 1, Frederick W Alt

Primary Identifier  MGI:2667593 Allele Type  Targeted
Attribute String  Null/knockout Gene  Prkdc
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 6 was disrupted by the insertion of a neomycin selection cassette. Shortened transcipts were detected in homozygous mutant ES cells by RT-PCR analysis, however neither normal or aberrantly sized protein was detected by Western blot analysis. Assays of cell extracts indicated an ablation of endogenous protein activity.
  • mutations:
  • Insertion
  • synonyms:
  • DNA-PKcs-,
  • DNA-PKcs<N>,
  • DNA-PKcs<N>,
  • DNA-PKcs-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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31 Publication categories

Trail: Allele