| Primary Identifier | IPR046352 | Type | Domain |
| Short Name | MTMR3_Pase_dom |
| description | This entry represents the phosphatase domain of Myotubularin-related protein 3 (Mtmf3). Proteins in this entry are specific to chordates. Mtmr3 is a phosphatase that acts on lipids with a phosphoinositol head-group such as phosphatidyl-inositol 3-phosphate and phosphatidyl-inositol 3,5-bisphosphate []. It may also de-phosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues []. This enzyme has shown to play a regulatory role in the regulation of abscission, the final step of mitosis [], and innate immune responses to viral DNA through the modulation of STING trafficking []. |
