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Protein Coding Gene : Dhx9 DExH-box helicase 9
Primary Identifier  MGI:108177 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  13211
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables regulatory region RNA binding activity. Involved in positive regulation of interleukin-18 production; pyroptosis; and regulation of defense response. Acts upstream of or within cellular response to heat and circadian rhythm. Located in nucleolus. Is expressed in several structures, including alimentary system; central nervous system; lung; salivary gland primordium; and sensory organ. Orthologous to human DHX9 (DExH-box helicase 9).
PHENOTYPE: Homozygotes die in embryonic stages with massive apoptotic cell death in embryonic ectodermal cells. [provided by MGI curators]
  • synonyms:
  • RNA helicase,
  • NDH II,
  • AI326842,
  • NDHII,
  • expressed sequence AI326842,
  • DExH-box helicase 9,
  • leukophysin,
  • Dhx9,
  • MGD-MRK-37216,
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 9,
  • Ddx9,
  • MGI:2138215,
  • RHA,
  • nuclear DNA helicase II
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Features --> Cross References

Genome

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2 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

14 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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