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Protein Coding Gene : Adarb2 adenosine deaminase, RNA-specific, B2

Primary Identifier  MGI:2151118 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  94191
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to act upstream of or within mRNA processing. Predicted to be located in nucleus. Predicted to be active in cytoplasm and nucleolus. Is expressed in several structures, including alimentary system; central nervous system; integumental system; limb; and sensory organ. Orthologous to human ADARB2 (adenosine deaminase RNA specific B2 (inactive)).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased anxiety-related behavior and impaired contextual learning and memory. [provided by MGI curators]
  • synonyms:
  • Adar3,
  • RED2,
  • adenosine deaminase, RNA-specific, B2,
  • Adarb2

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