Primary Identifier | IPR039731 | Type | Family |
Short Name | Rce1 |
description | Rce1 is an integral membrane, metal-dependent endoprotease localized to the endoplasmic reticulum that mediates the cleavage of the carboxyl-terminal three amino acids from CaaX proteins, such as Ras family of small GTPases, the gamma-subunit of heterotrimeric GTPases, nuclear lamins, and protein kinases and phosphatase []. It is classified as type II CAAX prenyl protease [, ]and is included in peptidase family M79. Its structure has been solved []. |