Primary Identifier | IPR006504 | Type | Family |
Short Name | Tscrpt_reg_Spx/MgsR |
description | Characterized members of this family include Spx and MgsR from Bacillus subtilis. Spx is a global transcription regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Induces the expression of a large number of genes in response to a variety of stress conditions, such as disulfide, heat and cell wall stress. It interacts with RNA polymerase [, ]. MgsR (modulator of the general stress response, also called YqgZ) provides a second level of regulation for more than a third of the proteins in the B. subtilis general stress regulon controlled by Sigma-B []. |