Primary Identifier | IPR023731 | Type | Family |
Short Name | Spx |
description | Spx is a global transcriptional regulator that plays a key role in stress response [, , , , , ]. It acts as an "anti-alpha"factor and interacts with the RNA polymerase alpha subunit C-terminal domain. RNA polymerase is therefore prevented from responding to certain activator proteins such as ResD and ComA []. Spx is a negative regulator of competence []. It was previously known as YjbD []. |