Primary Identifier | MGI:7435744 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Mertk |
Strain of Origin | C57BL/6N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology using sgRNA 5â-gGAATGGCCTGTGGTTGACT-3â (5â mismatch indicated by lowercase g) generated mice harboring a sequence with stop codons in all reading frames in exon 2. The stop cassette inserted at genomic position GRCm38/mm10 chr2:128,729,258 has the following sequence: 5â-cgcTAAgTGAcTGAccaccgc-3â (Stop codons in upper case, flanking homology sequences are not included). |