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Allele : Mertk<em1Minh> MER proto-oncogene tyrosine kinase; endonuclease-mediated mutation 1, Minhong Yan

Primary Identifier  MGI:7435744 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Mertk
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology using sgRNA 5’-gGAATGGCCTGTGGTTGACT-3’ (5’ mismatch indicated by lowercase g) generated mice harboring a sequence with stop codons in all reading frames in exon 2. The stop cassette inserted at genomic position GRCm38/mm10 chr2:128,729,258 has the following sequence: 5’-cgcTAAgTGAcTGAccaccgc-3’ (Stop codons in upper case, flanking homology sequences are not included).
  • mutations:
  • Insertion
  • synonyms:
  • MerTK<->,
  • MerTK<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele