Primary Identifier | MGI:97932 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 19775 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables virus receptor activity. Acts upstream of or within response to virus. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and plasma membrane. Is expressed in central nervous system; dorsal root ganglion; lower jaw molar; and neural retina. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human XPR1 (xenotropic and polytropic retrovirus receptor 1). PHENOTYPE: Homozygotes and heterozygotes for a variant from some wild Mus stocks, including M. spretus, support replication of xenotropic murine leukemia viruses and mink cell focus-forming murine leukemia viruses that are not replicated in most laboratory strains. [provided by MGI curators] |