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Protein Coding Gene : Xpr1 xenotropic and polytropic retrovirus receptor 1

Primary Identifier  MGI:97932 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  19775
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables virus receptor activity. Acts upstream of or within response to virus. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and plasma membrane. Is expressed in central nervous system; dorsal root ganglion; lower jaw molar; and neural retina. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human XPR1 (xenotropic and polytropic retrovirus receptor 1).
PHENOTYPE: Homozygotes and heterozygotes for a variant from some wild Mus stocks, including M. spretus, support replication of xenotropic murine leukemia viruses and mink cell focus-forming murine leukemia viruses that are not replicated in most laboratory strains. [provided by MGI curators]
  • synonyms:
  • suppressor of yeast G<a> deletion,
  • xenotropic and polytropic retrovirus receptor 1,
  • Sxv,
  • susceptibility to xenotropic virus,
  • MGD-MRK-14673,
  • Xpr1,
  • Rmc1,
  • receptor for MCF virus 1,
  • Syg1,
  • Rmc-1,
  • MGD-MRK-13899,
  • MGD-MRK-13898

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For