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Protein Coding Gene : Dbi diazepam binding inhibitor

Primary Identifier  MGI:94865 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  13167
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable benzodiazepine receptor binding activity; identical protein binding activity; and long-chain fatty acyl-CoA binding activity. Acts upstream of or within several processes, including behavioral fear response; lateral ventricle development; and long-term synaptic potentiation. Located in mitochondrion. Is expressed in brain and early conceptus. Orthologous to human DBI (diazepam binding inhibitor, acyl-CoA binding protein).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal fur and skin morphology at P16 and impaired metabolic changes at weaning with reduced growth and hepatic cholesterol synthesis. Mice homozygous for a different knock-out allele complete exhibit embryonic lethality around implantation. [provided by MGI curators]
  • synonyms:
  • Acbp,
  • Dbi,
  • diazepam-binding inhibitor,
  • MGI:107826,
  • MGD-MRK-36403,
  • endozepine,
  • EP,
  • acyl-CoA-binding protein,
  • MGD-MRK-8802,
  • diazepam binding inhibitor

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For