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Comment :

Type  MGI:General Description  total marrow cellularity is reduced already at 4-8 months of age and further reduced by 2-fold at 15-20 months of age 2- to 3-fold decrease in the frequency of all types of progenitor cells in the bone marrow with age; when adjusted for the reduction in total marrow cellularity, corresponds to a 4-fold reduction in total number of progenitor cells per femur