Primary Identifier | MGI:6857756 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Foxm1 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
description | The version of this allele that contains the neomycin selection cassette, Foxm1tm1Rhc, has been analyzed. |
molecularNote | A single loxP site was introduced into intron 3 and a floxed PGK-neo cassette was introduced downstream of exon 7 through homologous recombination. Cre-mediated recombination removed the loxP-flanked neomycin cassette leaving a single loxP site downstream of exon 7. Selected mice retained loxP sites flanking exons 4-7. |